What is really going on in our bodies these days?
Biological Signals After CV19: mRNA, Spike Protein & Exosomes
We were told the mRNA from cv19 vaccines breaks down quickly, and for most people, that seems to be true, in that they are feeling healthy and well.
But what about those reporting lingering symptoms, immune shifts or unusual fatigue, emotional changes, mental wellness challenges months and years after the CV19 vaccine?
Could the spike protein be hanging around longer than expected? And if so, why?
Could exosomes, tiny cellular messengers, be playing a role in how the spike protein is shared or signalled throughout the body? These aren’t fringe questions.
There is a deeper need to understand how the body processes novel vaccine technologies, and why not all human body responses are the same.
This article only provides some small insight based on my level of curiosity.
What Is mRNA and What Does It Do?
Messenger RNA (mRNA) is a fundamental component of human biology and has existed as long as life has utilised DNA. Every cell in your body constantly uses mRNA.
mRNA acts as a temporary messenger. DNA remains protected inside the cell nucleus, while mRNA carries a copied instruction out into the cell. That instruction is delivered to ribosomes, the cell’s protein-building machinery.
Ribosomes are where genetic instructions become physical matter.
How mRNA and Ribosomes Work Together
Under normal conditions, a cell identifies a need which could be: repair, growth, immune defence, hormone signalling or adaptation. A short section of DNA is copied into mRNA. That mRNA exits the nucleus and is read by ribosomes in the cytoplasm.
Ribosomes read the mRNA line by line and assemble amino acids in the correct order to build a specific protein. Once the protein is made, the mRNA is broken down and recycled.
Natural mRNA is tightly regulated. It is short-lived, context-specific and produced only as needed. Ribosomes do not decide what to build; they follow the instructions they are given.
Through this system, the body repairs tissue, produces enzymes, regulates hormones and neurotransmitters, mounts immune responses and maintains everyday metabolism.
Where Synthetic mRNA Enters the Picture
In the context of the cv19 vaccines, synthetic mRNA was introduced to deliver
a specific instruction: to produce the SARS-CoV-2 spike protein so the immune system could recognise it.
That synthetic mRNA enters cells and is read by ribosomes in the same way natural mRNA is. Ribosomes do not distinguish between natural and synthetic messages; they translate whatever instruction arrives.
The synthetic mRNA does not enter the cell nucleus and does not integrate into DNA. That distinction matters. And this is what we have been told.
What was assumed and communicated early on was that this synthetic mRNA would behave like natural mRNA: briefly present, tightly controlled and rapidly cleared. That assumption formed the basis of the original safety narrative.
The Biological Question That Actually Matters
The key issue is not whether mRNA or ribosomes exist, both are normal and essential parts of human biology.
What matters is how long a particular instruction remains present, how much protein ribosomes are instructed to produce, where in the body this activity occurs, how the immune system responds, and whether the body can return to baseline once signalling ends.
Ribosomes amplify whatever signal they are given. When signalling is brief, balance is restored. When it persists, the system can struggle to return to baseline.
Why This Matters for the Body Today
If signalling is brief and resolves naturally, ribosomes support healing and balance. The body responds, completes the task, and returns to baseline.
If signalling is prolonged or repeated, ongoing protein production places sustained demand on cellular energy, immune regulation, and repair systems, particularly in tissues that are already immune-active.
mRNA is the messenger. Ribosomes are the builders. They are ancient, precise and neutral. What determines outcomes is the instruction they receive, how long it persists, and if the body is able to resolve the signal and restore equilibrium afterwards. This distinction becomes especially important when considering the introduction of synthetic mRNA.
How Ribosomes Respond to Natural and Synthetic mRNA
Ribosomes are neutral molecular machines. Their role is to translate mRNA into protein. They do not assess where an mRNA message comes from, whether it is natural or synthetic, or whether the protein produced is beneficial or foreign. If a compatible mRNA is present in the cytoplasm, ribosomes will translate it.
Under normal conditions, ribosomes are constantly reading the body’s natural mRNA. mRNA is produced only when needed and cleared once the task is complete. The result is a dynamic balance: proteins are made as needed, then the system returns to baseline.
When synthetic mRNA is introduced into cells, it enters the same translational pathway. Ribosomes do not switch modes or prioritise one message over another. They read whatever instructions are available. In that sense, synthetic and natural mRNA are processed using the same cellular machinery.
Do Ribosomes “Choose” Between Messages?
Ribosomes do not choose between messages in the way we think of choice. There is no intent, priority system or hierarchy. Ribosomes just translate mRNA instructions that are present inside the cell.
Which proteins get made and in what amounts is determined earlier, at the level of cellular signalling. Cells only produce mRNA when they receive a signal to do so, such as during repair, immune activation or adaptation to stress. The strength and duration of that signal determine how many copies of a particular mRNA message are produced and how long those messages remain intact.
If more than one mRNA is present at the same time, ribosomes translate across all of them. They do not favour natural over synthetic, or repair over immune signals. Protein output is shaped by how much of a specific mRNA message is present, how stable it is before breaking down, how long the signal persists, and how much energy the cell has available to support the work.
This is not a conscious or selective process. It reflects the cell’s workload and capacity at that moment, how much it is being asked to do, and for how long.
What Happens During a Foreign or Immune Signal?
When the body encounters something foreign for example a pathogen or foreign protein, immune signalling increases. That signalling changes the cellular environment. Some mRNA messages are amplified, others are temporarily suppressed and resources are redirected toward immune defence.
In this context, ribosomes may spend more time translating proteins related to immune signalling, inflammation or antigen presentation. (An antigen is a protein or protein fragment that the immune system recognises and responds to).
This is a normal and necessary response in the short term.
Problems arise not because ribosomes “choose wrong,” but when signalling does not resolve, when the system stays activated longer than intended. Prolonged protein production, especially of immune-stimulating proteins, places sustained demand on cellular energy systems and can interfere with normal repair, regeneration and metabolic balance.
So Which “Wins” - Natural or Synthetic mRNA?
Neither “wins” in a competitive sense. Ribosomes do not defend the body or fight foreign material. That role belongs to the immune system. Ribosomes simply execute instructions. If a foreign or synthetic mRNA signal persists, ribosomes will continue to translate it alongside the body’s own messages for as long as it remains present.
The biological impact depends on signal duration, protein load, tissue distribution, and immune response. Not on ribosomal preference.
Why This Distinction Matters
It helps explain why outcomes can vary between individuals. Bodies differ in immune sensitivity, detox capacity, mitochondrial resilience, nutrient status and recovery ability. When signalling is brief and well-resolved, balance is restored. When signalling is prolonged or layered on top of existing stressors, the system can struggle to return to baseline.
Ribosomes translate instructions.
mRNA carries those instructions.
The immune system interprets the result.
Health outcomes depend on how long signals persist and if the body can resolve them - not on ribosomes “choosing sides.”
The Spike Protein - What It Is and Why It Matters
The spike protein is a structural protein found on the surface of coronaviruses.
It's called "spike" because it appears as protrusions or spikes on the ‘virus’ outer shell. The protein binds to a receptor on human cells called ACE2, which acts like a doorway for the virus to enter.
I will switch between using the terms “virus” and “foreign body.” To date, there is no conclusive scientific proof that a virus exists as a standalone, independently living entity that can be fully isolated and identified in the way most people assume.
If you’re interested in thoughtful, challenging perspectives on this topic, you may wish to explore the work of Dr Sam Bailey, who examines what she describes as virus-mania in modern medicine.
mRNA vaccines teach the body to make this spike protein (without the ‘virus’ itself) so the immune system can recognise and destroy the ‘virus’ if you’re ever exposed to the actual foreign body. In the lab, it appeared to be an effective training tool, but the presence of spike protein alone may trigger immune responses, even after the mRNA is gone. The idea that humans can and are playing around with the body’s natural processes is scary, but a current-day reality.
Why mRNA Breaks Down Quickly (But Spike Protein Might Not)
Synthetic mRNA is designed to degrade rapidly, as it’s made from the same unstable materials as natural mRNA. However, once the spike protein is produced, it may persist for longer, particularly if it is not quickly tagged and cleared by the immune system.
Studies have found spike protein fragments in blood or tissue weeks, months and years after vaccination in some people. This doesn’t necessarily mean the body is still making it, but rather that it hasn’t fully cleared it. In most people, immune clearance works efficiently. In others, it may be slower or incomplete.
So Why Is Spike Protein Still Detected in Some People?
Several possible mechanisms are being explored. In some individuals, protein clearance may be slower than expected. This can be influenced by immune function, metabolic health, inflammation and the body’s ability to break down and recycle proteins efficiently.
Some studies suggest that certain cells, including immune or endothelial cells, may retain spike protein or its fragments for longer periods. The extent and significance of this is still being investigated.
Another proposed mechanism involves exosomes. These are small signalling particles released by cells that can carry proteins or protein fragments to other tissues. Spike protein has been detected in exosomes in some research settings, raising the possibility of prolonged immune signalling.
Importantly, the presence of spike protein does not necessarily indicate ongoing mRNA activity. Protein persistence and immune signalling can outlast the original instruction. However, questions remain about how vaccine-generated proteins are processed and cleared over time in different individuals.
Exosomes: The Body’s Tiny Couriers
Exosomes are small, bubble-like vesicles released by nearly all cell types. They carry proteins, lipids, and genetic material between cells. Think of them as microscopic mail carriers that deliver molecular messages.
After mRNA vaccination, cells that produce spike protein may release exosomes containing parts of the spike protein. This could help alert the immune system,
but may also allow the protein to reach parts of the body far from the injection site.
In some cases, exosomes might prolong the presence of spike protein in circulation or tissues.
Exosomes are not inherently bad; they’re part of normal cell communication. But when they carry pro-inflammatory or poorly cleared proteins, they may play a role in long-term symptoms.
Lipid nanoparticles (LNPs)
LNPs are tiny fat-based carriers used to deliver genetic material, like mRNA, in vaccines such as Pfizer and Moderna’s cv19 shots.
Here's what you need to know about them:
Purpose: LNPs protect the fragile mRNA and help it enter human cells, where the mRNA instructs the cell to produce the spike protein (which then triggers an immune response).
Structure: Think of them like microscopic bubbles made of synthetic fats (lipids), often PEGylated (coated with polyethylene glycol) to increase stability.
Persistence: Some studies suggest LNPs can travel beyond the injection site, entering the bloodstream and reaching various tissues, including reproductive organs, liver, spleen, and brain.
Concerns: While meant to degrade, there’s ongoing debate about how long they persist in the body and whether they contribute to inflammation, immune activation, or cellular stress, particularly if detoxification pathways (liver, lymph, gut) are sluggish.
In a detox context, LNPs are considered part of the “toxic load” that the body may still be clearing months or even years later, especially in those with fatigue, cycle changes, or systemic inflammation.
Individual Variation - Why Everybody Responds Differently
Surprisingly, or not so surprisingly, not everyone processes vaccines or foreign proteins the same way. Factors that influence variation include:
Genetic differences in immune pathways
Hormonal status (e.g., postmenopausal women may respond differently)
Chronic inflammation or autoimmune conditions
Previous exposure to the virus
Dietary and lifestyle factors
Some individuals experience a natural immune response and clear the spike protein efficiently. Others suffer ongoing or long-term effects, sometimes amounting to chronic injury. In many cases, a slower or dysregulated immune response contributes to prolonged symptoms.
A growing number of people report changes in brain function, emotional regulation, and mental well-being, signs that suggest neurological involvement and disruption across the blood-brain barrier.
What We Know, What We Don’t, and Why It Matters
What we have been told:
This synthetic mRNA was not designed to enter the nucleus or alter DNA.
The body makes spike protein briefly, then breaks down the mRNA.
Most people clear the spike protein.
What’s still being studied:
Why some people show evidence of spike protein months, years later?
The role of exosomes in protein persistence and symptom distribution.
How to support the body in clearing spike protein more effectively.
What we don’t know:
How the mRNA injections respond to each body, with its inherent individual responses and immune system
Exosome ongoing transportation and messaging
The role of LNPs in spike protein persistence, other symptoms and symptom distribution
Persistence of spike protein production
The full ingredients of the vaccines
Understanding these processes is not to create fear; it’s about informed health.
For those with persistent symptoms, having a scientific explanation opens the door to appropriate support and care.
Decades of Research, Little Real-World Use
Before cv19, synthetic mRNA had not been used in any routinely approved or widely deployed vaccines.
mRNA technology had been researched for several decades in laboratories and early clinical studies. Scientists explored its potential for things like influenza, rabies, Zika, and cancer therapies. However, these efforts did not result in mRNA vaccines being fully approved for general use or rolled out at a population scale.
It may come as no surprise that the technology repeatedly faced challenges around stability, delivery into cells, inflammatory responses and unanswered questions about long-term effects.
The CV19 vaccines were the first time synthetic mRNA was authorised and used widely in humans, made possible by emergency-use pathways rather than the usual extended approval timelines. This meant large-scale deployment occurred before long-term, real-world outcome data could exist.
So while the underlying biology of mRNA was well understood, its mass use as a medical intervention was unprecedented.